Relevance of changes in blood fibrinolytic and coagulation parameters during thrombolytic therapy

Significance of coagulation parameters in the outcome of thrombolytic therapy

Disorders of the blood coagulation-fibrinolytic system

Most human cells have no direct contact with the external environment and their living conditions are ensured by blood. An essential criterion for normal blood circulation is the ability of the blood to arrest bleeding at sites of tissue injury and to prevent thrombus formation inside the blood vessels under normal conditions. The balance between these two extreme states is rigorously controlle...

Changes in blood acid-base balance parameters and coagulation profile during diarrhea in calves.

The purpose of this study was to investigate possible alterations in acid-base balance parameters and the coagulation profile in neonatal diarrheic calves. Twenty neonatal diarrheic and 20 clinically healthy neonatal calves aged between 1 week to 10 days were used. All blood samples were taken on the third day from the onset of diarrhea symptom. Venous blood samples were collected from each ani...

Changes in blood coagulation-related parameters in phenobarbital-treated rabbits.

The effects of repeated administration of phenobarbital (PB) on blood coagulation time were examined using male Japanese white SPF rabbits, which are widely used for toxicological studies. PB was administered to the rabbits by oral gavage for 2 weeks, at dose levels of 0, 12.5, 25 and 50 mg/kg/day. Blood was collected on Days 8 and 14 after each day's dosing to perform blood coagulation examina...

Blood coagulation and plasma fibrinolytic enzyme system pathophysiology in stroke.

Plasma fibrinogen chromatography is a method for quantification of high molecular weight fibrinogen complexes (HMWFC), native fibrinogen and other fibrinogen derivatives in plasma. Enchanced formation of fibrin, intravascular coagulation, thrombus formation, etc., are reflected by elevation of plasma HMWFC, and the method distinguishes between subjects with normal and pathological rates of fibr...